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    當前位置:首頁 > 技術文章 > listlabs 177B說明書

    listlabs 177B說明書

    更新時間:2018-12-10      點擊次數:2304

    list biological laboratories公司是世界的科研毒素試劑供應商,其毒素包括霍亂病毒,蛇毒,百日咳毒素等各類毒素,我公司常年低價供應,貨期快.有意者請. 百日咳毒素長期現(xiàn)貨供應,貨號181及180。

    listlabs 177B說明書

     

    炭疽毒素Anthrax Toxins

    炭疽桿菌是炭疽病的病原體。炭疽桿菌產生的主要毒力因子是γ連接的聚-D-谷氨酸膠囊和由三種成分組成的外毒素,保護性抗原(PA),致死因子(LF)和水腫因子(EF)。這些蛋白質不是單*毒的,而是以二元組合起作用。PA(細胞結合成分)與LF(酶部分之一)的復合物被稱為“致死毒素”并可導致死亡。PA和酶促EF一起引起皮膚水腫。分泌后,PA被膜肽酶切割,使63kDa羧基末端片段寡聚化成七聚體。切割是暴露EF和LF的結合位點的必要步驟。組裝的PA復合物和相關的LF或EF通過胞吞作用進入細胞。PA介導LF和EF向細胞質的轉移,其中這些酶識別并蛋白水解其靶標。LF組分是一種鋅依賴性金屬蛋白酶,可裂解絲裂原活化蛋白激酶激酶(MAPKK),從而削弱其功能,從而阻斷MAPK信號通路。EF是鈣調蛋白依賴性腺苷酸環(huán)化酶,其在細胞中產生過量的環(huán)AMP,導致水腫。目前的研究集中于開發(fā)有效的疫苗以及篩選LF酶活性的有效抑制劑。

    含有炭疽LF切割位點的FRET肽底物可作為MAPKKide®獲得,并可用于評估LF的酶活性。

     

    炭疽毒素

    (炭疽保護性抗原和衍生物)

    炭疽保護性抗原片段(PA 20)
    炭疽芽孢桿菌

    炭疽毒素

    (炭疽保護性抗原和衍生物)

    保護性抗原(PA)是炭疽毒素的受體結合成分。原始的83kDa蛋白質被細胞弗林蛋白酶樣蛋白酶切割,形成活化的63kDa單體PA63。在這種形式中,PA63與其他PA63分子結合形成環(huán)狀七聚體。PA63還具有對于與細胞表面上形成的孔相鄰的酶LF和EF特異性的結合位點,用于易位。對于醉酒細胞,PA應與EF或LF一起使用約7倍過量。

    List Labs提供三種不同大小的PA,產品#171是未切割的83kDa蛋白質,產品#174和175是PA63,它們已被激活和純化,PA63分別與FITC綴合。另外,我們提供從PA,PA20,產品#177切割的約20kDA片段

     

     

    #177A(50 ug) - $ 340.00

     #177B(0.25毫克) - $ 610.00

     

      

     

    貨號

    品名

     規(guī)格

    價格

    list104

    Cholera Toxin B Subunit (Choleragenoid) in low salt1

    0.5mg

    4930

    list106

    Cholera Toxin B Subunit Fluorescein Isothiocyanate Conjugate (BFITC)

    0.2mg

    9775

    list112

    Cholera Toxin B Subunit Biotin

    0.2mg

    9775

    list122

    Enterotoxin Type B from Staphylococcus aureus1,3

    0.5mg

    7225

    list123

    Enterotoxin Type B Toxoid from Staphylococcus aureus  1,3

    0.25mg

    8075

    list139

    Botulinum Neurotoxin Type B Toxoid

    10µg

    6800

    list150

    Diphtheria Toxin, unnicked from Corynebacterium diphtheriae

    1mg

    11050

    list151

    Diphtheria Toxoid, from Corynebacterium diphtheriae

    0.5mg

    10625

    list153

    Toxin A Toxoid from Clostridium difficile

    100µg

    11900

    list156

    Pasteurella Multocida Toxin

    50µg

    8075

    list160

    Exotoxin A from Pseudomonas aeruginosa

    1mg

    4420

    list161

    Shiga Toxin 1 from Escherichia coli1,4,8

    10µg

    11900

    list162

    Shiga Toxin 2 from Escherichia coli1,4,8

    10µg

    11050

    list174

    Anthrax Protective Antigen, Activated (PA 63) from Bacillus anthracis

    0.5mg

    9350

    list175

    Anthrax PA 63 - Fluorescein Isothiocyanate Conjugate (PAFITC)

    50µg

    7225

    list180

    Pertussis Toxin Islet-Activating Protein Lyophilized in buffer

    50µg

    5525

    list181

    Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free)

    50µg

    5525

    list184

    Pertussis Toxin Mutant

    50µg

    5525

    list186

    FIMBRIAE 2/3 from B. pertussis

    50µg

    5950

    list187

    Pertactin from Bordetella pertussus (69 kDa Protein)

    50µg

    4590

    list193

    Tetanus Toxin C Fragment

    10µg

    9350

    list201

    LPS from Escherichia coli O111:B4

    5mg

    3230

    list206

    LPS, Escherichia coli 0157:H7

    10.0mg

    4760

    list225

    LPS from Salmonella typhimurium

    5mg

    2890

    list301

    LPS from Escherichia coli J5 (Rc)

    5mg

    2890

    list302

    LPS from Escherichia coli K12, D31m4 (Re)

    5mg

    2890

    list304

    LPS from Salmonella minnesota R595 (Re)

    5mg

    2890

    list314

    LPS from Escherichia coli K12 strain LCD25

    1mg

    2890

    list400

    HPT™ LPS, highly purified from Bordetella Pertussis 165

    1mg

    5100

    list401

    Lipid A monophosphoryl from Salmonella minnesota R595

    1mg

    3400

    list421

    Ultra Pure LPS from Escherichia coli O111:B4

    1mg

    3570

    list423

    Ultra Pure LPS from Escherichia coli O55:B5

    1mg

    3570

    list433

    LISTÔ HPTÔ, LPS, highly purified Escherichia coli O113 LPS

    1mg

    4080

    list434

    Ultra Pure LPS from Salmonella minnesota R595 (Re)

    1mg

    3400

    list520

    SNAPtide® Peptide Substrate (o-Abz/Dnp)  (U.S. Patent #6,504,006)

    200nmoles

    9775

    list521

    SNAPtide® Peptide Substrate (FITC/DABCYL)  (U.S. Patent #6,504,006)

    200nmoles

    8500

    list523

    SNAPtideÒ Peptide Substrate flP6 (DABCYL/5-IAF), U.S. Patent Pending #61/252,675

    200nmoles

    8500

    list525

    Control Peptide for SNAPtideÒ #520

    200nmoles

    8500

    list526

    Control Peptide for SNAPtide® #521

    200nmoles

    8500

    list528

    Unquenched Calibration Peptide for SNAPtide®  521

    50nmoles

    2890

    list529

    Unquenched Calibration Peptide for SNAPtide®  520

    50nmoles

    2890

    list530

    MAPKKide® Peptide Substrate (o-Abz/Dnp)

    200nmoles

    5100

    list531

    MAPKKide® Peptide Substrate  (DABCYL/FITC)

    200nmoles

    5100

    list532

    MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor

    100nmoles

    4250

    list539

    Unquenched Calibration Peptide for MAPKKideÒ 530

    50nmoles

    2890

    list540

    VAMPtide® Peptide Substrate (o-Abz/Dnp)

    200nmoles

    8500

    list541

    VAMPtide® Peptide Substrate (FITC/DABCYL)

    200nmoles

    8500

    list542

    VAMPtide® Peptide Substrate (PL 150, Pya/Nop)

    200nmoles

    8500

    list549

    Calibration  Fluorophore for VAMPtideÒ 540

    100nmoles

    2890

    list550

    SNAP Etide® Peptide Substrate (o-Abz/Dnp)

    100nmoles

    6800

    list560

    SYNTAXtideÒ Peptide Substrate (o-Abz/Dnp) for C. botulinum Type C

    200nmoles

    8500

    list703

    Anti-Cholera Toxin B Subunit (Goat)

    0.1ml

    3060

    list752

    Anti-Toxin A from Clostridium difficile (Goat)

    0.5ml

    3230

    list760

    Anti-Exotoxin A (Goat)

    0.5ml

    3400

    list781

    Anti-Protective Antigen from Bacillus anthracis (Goat) affinity purified, Liquid6,7

    0.1mg

    7055

    list100B

    Cholera Toxin (Azide Free)1

    1mg

    3400

    list101B

    Cholera Toxin1

    1mg

    3400

    list101C

    Cholera Toxin1

    2mg

    5355

    list116L

    Alpha Toxin from C. septicum4,6,7

    50µg

    4930

    list126A

    Epsilon Toxin from C. perfringens1,4,8

    0.1mg

    5950

    list128A

    Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3

    10µg

    2890

    list128C

    Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3

    100µg

    5440

    list130A

    Botulinum Neurotoxin Type A from Clostridium botulinum1,3

    10µg

    5440

    list130B

    Botulinum Neurotoxin Type A from Clostridium botulinum1,3

    100µg

    13600

    list133L

    Botulinum Neurotoxin Type A Toxoid, Liquid6,7

    10µg

    5440

    list136A

    Botulinum Neurotoxin Type B. from Clostridium botulinum 1,3

    10µg

    5100

    list136B

    Botulinum Neurotoxin Type B, from Clostridium botulinum1,3

    100µg

    17000

    list138A

    Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3

    10µg

    2890

    list138B

    Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3

    100µg

    7225

    list140A

    Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3

    10µg

    2890

    list140B

    Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3

    100µg

    8925

    list141A

    Botulinum Neurotoxin Type E, Nicked, from Clostridium botulinum1,3

    10µg

    8075

    list146A

    Botulinum Neurotoxin Type D, Nicked, Recombinant from Clostridium botulinum1,3

    10µg

    5355

    list149A

    Diphtheria Toxin CRM Mutant

    0.25 mg

    8500

    list152C

    Toxin A from Clostridium difficile

    100µg

    9010

    list154A

    Toxin B Toxoid from Clostridium difficile

    20µg

    2890

    list15

    Toxin B  from Clostridium difficile

    2µg

    2890

    list155B

    Toxin B  from Clostridium difficile

    20µg

    8500

    list155C

    Toxin B  from Clostridium difficile

    200µg

    15300

    list155L

    Toxin B from Clostridium difficile, Liquid6,7

    50µg

    9860

    list157A

    Binary  Toxin from Clostridium difficile, A Subunit

    20µg

    5950

    list158A

    Binary  Toxin from Clostridium difficile, B Subunit

    40µg

    5950

    list159A

    Glutamate Dehydrogenase (GDH) from Clostridium difficile6,7

    0.1mg

    4930

    list169A

    Anthrax Lethal Factor (LF-A) , Recombinant from Bacillus anthracis Native Sequence

    0.1mg

    3060

    list169B

    Anthrax Lethal Factor (LF-A),Recombinant from Bacillus anthracis Native Sequence

    1mg

    12750

    list169L

     Anthrax Lethal Factor (LF-A),Recomb.from Bacillus anthracis 5,7

    0.2 mg

    5950

    list171E

    Anthrax Protective Antigen (PA), Recombinant from Bacillus anthracis

    0.5mg

    8755

    list172B

    Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis

    1mg

    12750

    list172C

    Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis

    10mg

    39525

    list172L

    Lethal Factor, Recomb from Bacillus anthracis, froz liq 5,7

    1.0 mg

    12750

    list173B

    Anthrax Edema Factor (EF), Recombinant Mutant S447N  from Bacillus anthracis

    0.5mg

    16150

    list176A

    Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis

    0.1mg

    5100

    list176B

    Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis

    1mg

    16150

    list177A

    Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis

    50µg

    5950

    list177B

    Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis

     0.25mg

    11050

    list178A

    Anthrax Edema Factor (EF), Recombinant from Bacillus anthracis

    0.1mg

    2890

    list179A

    Pertussis Toxin Islet Activating Protein (in glycerol)6,7

    50µg

    4845

    list188L

    Adenylate Cyclase Toxin from B. pertussis, Recombinant, Frozen Liquid5,7

    50µg

    5270

    list190A

    Tetanus Toxin2

    25µg

    2890

    list190B

    Tetanus Toxin2

    100µg

    9350

    list191A

    Tetanus Toxoid

    25µg

    4675

    list191B

    Tetanus Toxoid

    100µg

    13600

    list196A

    C-fragment, FITC Conjugate

    10µg

    6800

    list203A

    LPS, Escherichia coli O55:B5

    2.5 mg

    3060

    list500A

    SNAP-25 Recomb Protein Substrate for C. botulinum Type A and E Neurotoxin

    100µg

    5525

    list510A

    GST Synaptobrevin-2 Protein Recomb. Protein Substrate for C. botulinum Type B,D and F

    100µg

    5950

    list610A

    Botulinum Neurotoxin Type A Light Chain, Recombinant1

    10µg

    4760

    list611A

    Botulinum Neurotoxin Type A Light Chain, GST Fusion, Recombinant1

    15µg

    4760

    list612A

    Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain1

    50µg

    4760

    list613A

    Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion1

    50µg

    4760

    list620A

    Botulinum Neurotoxin Type B Light Chain, Recombinant1

    10µg

    8500

    list622A

    Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain1

    50µg

    4760

    list623A

    Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion1

    50µg

    4760

    list62

    Botulinum Neurotoxin Type C Light Chain, Recombinant1

    10µg

    8500

    list630A

    Botulinum Neurotoxin Type D Light Chain, Recombinant1

    10µg

    5695

    list650A

    Tetanus Toxin Light Chain, Recombinant

    10µg

    3825

    list690B

    Receptor for C. botulinum Type A Neurotoxin GST-SV2c luminal domain
    (U.S. Patent #8,476,024)

    100nmoles

    6800

    list730A

    Anti-Botulinum Neurotoxin, Type A (Chicken lgY), Liquid6,7

    0.1mg

    5610

    list731L

    Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Liquid6,7

    0.1mg

    5950

    list736A

    Anti-Botulinum Type B (Chicken lgY), Liquid6,7

    0.1mg

    5950

    list753A

    Anti-Clostridium difficile Toxin A (Chicken lgY), Liquid6,7

    0.1mg

    5780

    list754A

    Anti-Clostridium difficile Toxin B (Chicken lgY), Liquid6,7

    0.1mg

    5780

    list756A

    Anti-Clostridium difficile Glutamate Dehydrogenase, lgY, Liquid6,7

    0.1mg

    5780

    list757A

    Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY), Liquid6,7

    0.1mg

    5780

    list758A

    Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7

    0.1mg

    5780

    list759A

    Biotinylated Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7

    0.1mg

    5780

    list761L

    Anti-Shiga Toxin 1 (Rabbit), lgG, Liquid6,7

    0.5mg

    3400

    list765L

    Anti-Shiga Toxin 2 (Rabbit), IgG, Liquid6,7

    0.5mg

    2890

    list766L

    Anti-Shiga Toxin, Camelid Antibody, VHH, Liquid6,7

    0.5mg/ml

    5950

    list768L

    Biotinylated Anti-Lethal Factor from B. anthracis, IgY, Liquid6,7

    0.1mg

    5950

    list769B

    Anti-Lethal Factor from Bacillus anthracis (Chicken lgY), Liquid6,7

    0.2mg

    8500

    list771B

    Anti-Protective Antigen from Bacillus anthracis (Goat)

    1mg

    2890

    list772B

    Anti-Lethal Factor from Bacillus anthracis (Goat)

    1.0 mg

    2890

    list773L

    Anti-Edema Factor from Bacillus anthracis (Goat), Liquid6,7

    1mg

    2890

     

     

     

    Listlabs中國代理,Listlabs上海代理,Listlabs北京代理,Listlabs廣東代理,Listlabs江蘇代理Listlabs湖北代理,Listlabs天津代理,Listlabs黑龍江代理,Listlabs湖南代理Listlabs內蒙古代理,Listlabs吉林代理,Listlabs福建代理,Listlabs江蘇代理,Listlabs浙江代理,Listlabs四川代理,Listlabs代理,

     

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